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The drug abuse of John F Kennedy
...In his riveting volume In Sickness and In Power, former Foreign Secretary and medic David Owen reviews the health and medication of leaders over the last century. The chapter on Kennedy is jaw-dropping.

Owen starts by convincingly asserting that Kennedy was much sicker than is commonly appreciated and certainly much sicker than was appreciated at the time. His Addison's disease was very debilitating and needed constant attention....

...Central to Owen's account is the idea that the administration of drugs to Kennedy for these various ailments was out of control.

In particular, without the knowledge of his other doctors and at the same time as they were giving him other drugs, he was being tended to by Max Jacobson, a doctor known as "Dr Feelgood" because of his reputation as a provider of amphetamines and pep pills. In time Jacobson's drug treatment became almost a recreational drug for Kennedy. Jacobson was later struck off.

Owen shows that is quite likely that Dr Feelgood, specially flown to Vienna, injected Kennedy with intravenous amphetamine just before he met Khrushchev....